Table 1 Genes and probe sets used to define the MKS and ERS.

From: Breast cancers with high proliferation and low ER-related signalling have poor prognosis and unique molecular features with implications for therapy

Symbol

Probe set

Description

Mitosis Kinase Score (MKS)

 PLK1

202240_at

polo-like kinase 1 (Drosophila)

 CDK1

203213_at

cyclin-dependent kinase 1

 BUB1B

203755_at

budding uninhibited by benzimidazoles 1 homolog beta (yeast)

 NEK2

204641_at

NIMA (never in mitosis gene a)-related kinase 2

 TTK

204822_at

TTK protein kinase

 MELK

204825_at

maternal embryonic leucine zipper kinase

 PLK4

204887_s_at

polo-like kinase 4 (Drosophila)

 CHEK1

205394_at

CHK1 checkpoint homolog (S. pombe)

 AURKA

208079_s_at

aurora kinase A

 AURKB

209464_at

aurora kinase B

 BUB1

209642_at

budding uninhibited by benzimidazoles 1 homolog (yeast)

 PBK

219148_at

PDZ binding kinase

Estrogen-related score (ERS)

 BCL2

203685_at

B-cell CLL/lymphoma 2

 ESR1

205225_at

estrogen receptor 1

 PGR

208305_at

progesterone receptor

 SCUBE2

219197_s_at

signal peptide, CUB domain, EGF-like 2