Fig. 3: Rationale for combination therapy in oncology. | British Journal of Cancer

Fig. 3: Rationale for combination therapy in oncology.

From: Unlocking hidden potential: advancements, approaches, and obstacles in repurposing drugs for cancer therapy

Fig. 3

The use of multiple drugs can target the inter-tumoural heterogeneity between patients, intra-tumoural heterogeneity within the same tumour (including the cancer stem cell subpopulation). Multiple drugs also target multiple pathways which may be redundant or compensatory allowing full cessation of proliferation, invasion and metastasis. Created using Biorender, May 2023.

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