Table 2 Frequency of treatment-related adverse events and laboratory abnormalities with >10% incidence.
Event | Any grade | Grade ≥ 3 |
|---|---|---|
Any event—no. (%) | 48 (94) | 15 (29) |
Any cause serious event—no. (%) | 15 (29) | 15 (29) |
Most common events—no. (%) | ||
Fatigue | 32 (63) | 2 (4) |
Nausea | 30 (59) | 5 (10) |
Hypertension | 16 (31) | 5 (10) |
Vomiting | 16 (31) | 3 (6) |
Anorexia | 13 (25) | 0 |
Headache | 12 (24) | 0 |
Diarrhoea | 11 (22) | 0 |
Constipation | 10 (20) | 0 |
Weight loss | 7 (14) | 1 (2) |
Dysgeusia | 6 (12) | 0 |
Myalgia | 5 (10) | 0 |
Laboratory abnormalities—no. (%) | ||
Platelet count decreased | 17 (33) | 0 |
Anaemia | 14 (27) | 1 (2) |
Proteinuria | 14 (27) | 0 |
Lymphocyte count decreased | 8 (16) | 1 (2) |
Neutrophil count decreased | 8 (16) | 0 |
Hypoalbuminemia | 6 (12) | 0 |
Creatinine increased | 5 (10) | 0 |
