Fig. 4: Recurrence rates based on the postoperative evaluation of serum p53 antibody responses.

Kaplan–Meier analysis of cumulative recurrence rates was assessed based on the p53 antibody status at 12 months (a) and 3 months (b) after surgery. HRs and 95% CIs were calculated using the Cox proportional hazard model. P values were calculated using the two-sided log-rank test. Percentages of patients with or without recurrence based on p53 antibody status at 12 months (c) and 3 months (d) after surgery. P values were calculated using a two-sided chi-squared test comparing the distribution of factors between the two columns (positive vs negative). The sensitivity and specificity for postoperative recurrence assessed by p53 positivity are shown below the graph.