Fig. 4: The proposed model describes the poor prognosis of HPV-positive HNSCC.
From: Navigating therapeutic strategies: HPV classification in head and neck cancer

HNSCC patients with high HPV genome integration show reduced HPV gene expression and lowered infiltration of T cells that result in unfavourable clinical outcomes similar to HPV-positive HNSCC. HPV human papillomavirus, HNSCC head and neck cancer squamous cell carcinoma.