Table 2

From: UK guidelines for the management of soft tissue sarcomas

Key recommendations: clinical presentation, referral and assessment:

1) Any patient with an unexplained lump that is increasing in size, should be considered for a direct access ultrasound scan to be performed within 2 weeks.

2) Consider a suspected cancer pathway referral for adults if they have ultrasound scan findings that are suggestive of soft tissue sarcoma or if ultrasound findings are uncertain and clinical concern persists.

3) Any retroperitoneal or intra-abdominal mass with imaging appearances suggestive of a soft tissue sarcoma should be referred to a specialist MDT before biopsy or surgical treatment.

4) All patients with a suspected STS should be managed by a specialist Sarcoma MDT as specified in the NICE guidance

5) A pre-treatment histopathological diagnosis should be made, if possible, by percutaneous core biopsy, which should be reviewed by a specialist sarcoma pathologist for diagnostic confirmation, and appropriate molecular and genomic analysis.

6) Cross-sectional imaging of the primary tumour, usually in the form of magnetic resonance imaging (MRI) is recommended prior to definitive surgery.

7) Imaging of the thorax by CT scan for lung metastases should be performed prior to radical treatment. Further staging may be considered depending on subtype and location of the sarcoma.