Fig. 3: Schematic polar representation of the distribution of peak times of selected rhythmic immune functions involved in antitumor immunity in rodent models over 24 h.
From: Why does circadian timing of administration matter for immune checkpoint inhibitors’ efficacy?
Peak time data are shown in three key compartments, i.e. bloodstream [red], lymph nodes [green], and tumor immune microenvironment [purple]). The circle in the center depicts the light-dark synchronization schedule of nocturnally active mice or rats. HALO Hours After Light Onset.
