Table 1 Characteristics of the study population and univariate associations with diagnostic interval.

From: The effect of comorbidities on diagnostic interval for lung cancer in England: a cohort study using electronic health record data

 

n (%)

Median (IQR) diagnostic interval (days)

p valuea

Sex

 Male

6884 (58.0)

133 (43, 263)

<0.001

 Female

4986 (42.0)

152 (51, 278)

 

Age (y)

76.2 (7.5)b

0.705 (0.144)c

<0.001

Year of diagnosis

 <2000

835 (7.0)

121 (42, 261)

<0.001

 2000–2004

2586 (21.8)

117 (38, 251)

 

 2005–2009

3663 (30.9)

134 (44, 266)

 

 2010–2014

3325 (28.0)

168 (55, 287)

 

 2015–2019

1461 (12.3)

161 (56, 280)

 

Number of CD conditions

 None

3958 (33.3)

101 (36, 241)

<0.001

 One

4017 (33.8)

146 (49, 272)

 

 Two

2500 (21.1)

162 (55, 279)

 

 Three or more

1395 (11.8)

196 (80, 298)

 

Number of AE conditions

 None

5785 (48.7)

90 (34, 224)

<0.001

 One

4242 (35.7)

164 (56, 281)

 

 Two or more

1843 (15.5)

246 (137, 320)

 

Number of consultations

 Usual frequency (per y)

10 (5, 17)d

2.41 (0.09)c

<0.001

 Increase before diagnosis

 Yes 1

9039 (76.1)

139 (47, 269)

0.853

 No 0

2831 (23.9)

143 (43, 273)

 

IMD

 1

1321 (11.1)

1.44 (0.79)c

0.070

 2

1795 (15.1)

  

 3

2156 (18.2)

  

 4

2824 (23.8)

  

 5

3774 (31.8)

  

Presenting clinical problem

 Cough

3112 (26.2)

146 (51, 276)

<0.001

 Dyspnoea

2582 (21.8)

172 (58, 285)

 

 Chest infection

2271 (19.1)

173 (68, 285)

 

 Chest pain

1014 (8.5)

113 (44, 245)

 

 Fatigue

728 (6.1)

146 (49, 266)

 

 Thrombocytosis

622 (5.2)

92 (35, 249)

 

 Multiple

545 (4.6)

133 (35, 268)

 

 Haemoptysis

450 (3.8)

37 (21, 83)

 

 Weight loss

399 (3.4)

56 (24, 184)

 

 Other

147 (1.2)

48 (26, 158)

 

Ethnic Group

 White

10625 (89.5)

146 (49, 273)

0.100

 Other

101 (0.9)

186 (70, 278)

 

 Missing

1144 (9.6)

  

Smoking status

 Current or former smoker

10047 (84.6)

150 (49, 276)

<0.001

 Non-smoker

1366 (11.5)

117 (43, 237)

 

 Missing

457 (3.9)

  

BMI category

 Underweight

489 (4.1)

198 (72, 298)

<0.001

 Normal weight

4351 (36.7)

147 (47, 274)

 

 Overweight

3687 (31.1)

135 (47, 268)

 

 Obese

1898 (16.0)

156 (55, 280)

 

 Missing

1445 (12.2)

  

Alcohol drinking

 Current drinker

7939 (66.9)

140 (47, 268)

<0.001

 Former drinker

1319 (11.1)

182 (64, 294)

 

 Non drinker

1186 (10.0)

156 (53, 281)

 

 Missing

1426 (12.0)

  
  1. ap value by Mann–Whitney U test or Kruskal–Wallis as appropriate b - mean (sd).
  2. bmean (sd).
  3. cB(SE).
  4. dmedian (IQR).