Table 4 Comparison of the waist circumference-years metrics, single waist circumference and body mass index using Harrell’s C-statistic, ARIC.
Characteristic | (a) Harrell’s C-statistic (95% CI) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
WC-years | Single WC | Difference in c-statistic between single WC vs WC-years | Single BMI | Difference in c-statistic between single BMI vs WC-years | Difference in c-statistic between single BMI vs single WC | Cumulative degree of excess WC | Cumulative duration of excess WC | Difference in c-statistic between cumulative WC duration and WC degree | |
Men | |||||||||
All cancers | 0.587 (0.578,0.597) | 0.585 (0.576,0.595) | –0.002 (-0.007,0.002) | 0.584 (0.575,0.594) | –0.003 (-0.008,0.002) | –0.001 (–0.004,0.002) | 0.588 (0.578,0.597) | 0.585 (0.576,0.595) | –0.002 (–0.008,0.004) |
OR-cancers | 0.581 (0.562,0.601) | 0.580 (0.560,0.599) | –0.002 (-0.013,0.010) | 0.578 (0.558,0.598) | –0.004 (-0.015,0.008) | –0.002 (–0.011,0.007) | 0.581 (0.562,0.602) | 0.572 (0.553,0.592) | –0.009 (–0.023,0.004) |
NOR-cancers | 0.593 (0.582,0.604) | 0.592 (0.582,0.603) | –0.001 (-0.011,0.009) | 0.593 (0.582,0.603) | –0.001 (-0.010,0.009) | 0.000 (–0.007,0.008) | 0.593 (0.582,0.604) | 0.592 (0.582,0.603) | –0.000 (–0.008,0.007) |
NOR-cancers excluding lung and prostate | 0.600 (0.583,0.619) | 0.600 (0.583,0.618) | –0.000 (-0.008,0.007) | 0.600 (0.582,0.618) | –0.001 (-0.008,0.007) | –0.000 (–0.005,0.004) | 0.600 (0.583,0.619) | 0.599 (0.581,0.617) | –0.001 (–0.010,0.007) |
Colorectal | 0.638 (0.607,0.670) | 0.630 (0.600,0.662) | –0.007 (-0.025,0.010) | 0.629 (0.599,0.661) | –0.009 (-0.028,0.011) | –0.001 (–0.014,0.011) | 0.638 (0.607,0.670) | 0.629 (0.598,0.661) | –0.009 (–0.029,0.011) |
Pancreas | 0.644 (0.596,0.696) | 0.643 (0.595,0.695) | 0.016 (-0.020,0.051) | 0.644 (0.595,0.696) | 0.027 (-0.016,0.070) | 0.011 (–0.009,0.031) | 0.644 (0.596,0.696) | 0.641 (0.592,0.693) | 0.032 (–0.018,0.084) |
Kidney | 0.655 (0.606,0.707) | 0.657 (0.609,0.710) | –0.001 (-0.005,0.003) | 0.653 (0.606,0.704) | –0.001 (-0.005,0.004) | 0.001 (–0.003, 0.004) | 0.655 (0.606,0.707) | 0.707 (0.658,0.760) | –0.004 (–0.014,0.008) |
Bladder | 0.612 (0.569,0.657) | 0.627 (0.585,0.672) | 0.003 (-0.025, 0.030) | 0.638 (0.596,0.684) | –0.007 (-0.029,0.025) | –0.005 (–0.019,0.010) | 0.615 (0.572,0.661) | 0.648 (0.604,0.694) | 0.053 (0.004,0.102) |
Lung | 0.722 (0.701,0.743) | 0.730 (0.709,0.752) | 0.008 (-0.003,0.019) | 0.739 (0.717,0.761) | 0.017 (-0.000,0.034) | 0.009 (0.001,0.017) | 0.722 (0.701,0.743) | 0.724 (0.703,0.745) | 0.002 (–0.001,0.005) |
Prostate | 0.588 (0.573,0.603) | 0.588 (0.574,0.603) | 0.000 (-0.001,0.002) | 0.588 (0.576,0.603) | 0.000 (-0.002,0.002) | 0.000 (–0.001,0.001) | 0.588 (0.573,0.603) | 0.588 (0.573,0.603) | 0.000 (–0.003,0.003) |
Metastatic Prostate | 0.573 (0.525,0.626) | 0.585 (0.534,0.640) | 0.012 (-0.033,0.057) | 0.588 (0.535,0.647) | 0.015 (-0.047,0.077) | 0.003 (–0.032,0.039) | 0.573 (0.525,0.626) | 0.552 (0.511,0.597) | –0.021 (–0.097,0.055) |
Women | |||||||||
All cancers | 0.576 (0.565,0.586) | 0.579 (0.568,0.590) | 0.003 (–0.004,0.011) | 0.578 (0.567,0.588) | 0.002 (-0.007,0.011) | –0.001 (–0.010,0.007) | 0.579 (0.569,0.590) | 0.578 (0.568,0.589) | –0.001 (–0.014,0.011) |
OR-cancers | 0.577 (0.564,0.589) | 0.574 (0.562,0.570) | –0.002 (–0.013,0.009) | 0.568 (0.556,0.581) | –0.008 (-0.019,0.003) | –0.006 (–0.014,0.003) | 0.577 (0.564,0.590) | 0.575 (0.562,0.588) | –0.0022 (–0.016,0.012) |
NOR-cancers | 0.628 (0.611,0.644) | 0.628 (0.612,0.645) | 0.001 (-0.002,0.003) | 0.629 (0.613,0.645) | 0.001 (-0.002,0.005) | 0.001 (–0.001,0.002) | 0.628 (0.611,0.644) | 0.629 (0.612,0.645) | 0.001 (–0.002,0.004) |
NOR-cancers excluding lung | 0.578 (0.560,0.597) | 0.582 (0.565,0.601) | 0.005 (-0.003,0.012) | 0.588 (0.571,0.607) | 0.011 (-0.000,0.022) | 0.006 (0.000,0.013) | 0.5782 (0.560,0.597) | 0.579 (0.561,0.598) | 0.001 (–0.004,0.006) |
Colorectal | 0.618 (0.588,0.650) | 0.590 (0.559,0.621) | –0.029 (–0.051, –0.006) | 0.586 (0.556,0.618) | –0.032 (–0.061,–0.004) | –0.004 (–0.015,0.008) | 0.617 (0.587,0.649) | 0.617 (0.586,0.650) | –0.001 (–0.028,0.027) |
Pancreas | 0.622 (0.565,0.685) | 0.625 (0.568,0.688) | 0.003 (–0.015,0.021) | 0.614 (0.559,0.674) | –0.008 (–0.041,0.025) | –0.011 (–0.047,0.025) | 0.622 (0.565,0.685) | 0.628 (0.571,0.690) | 0.006 (–0.036,0.048) |
Kidney | 0.653 (0.596,0.715) | 0.661 (0.601,0.727) | 0.008 (–0.023,0.040) | 0.656 (0.596,0.719) | 0.002 (–0.015,0.019) | –0.007 (–0.034,0.021) | 0.654 (0.597,0.716) | 0.653 (0.591,0.723) | –0.001 (–0.061,0.060) |
Lung | 0.761 (0.733,0.789) | 0.761 (0.733,0.789) | 0.000 (–0.001,0.001) | 0.761 (0.733,0.789) | 0.000 (–0.001,0.002) | –0.000 (–0.002,0.002) | 0.761 (0.733,0.789) | 0.762 (0.735,0.790) | 0.007 (–0.001,0.004) |
Endometrial | 0.687 (0.638,0.739) | 0.710 (0.662,0.760) | 0.023 (–0.008,0.054) | 0.697 (0.650,0.746) | 0.010 (–0.021,0.041) | –0.013 (–0.036,0.010) | 0.6883 (0.64,0.741) | 0.676 (0.632,0.723) | –0.012 (–0.042,0.017) |
Ovarian | 0.621 (0.567,0.680) | 0.626 (0.571,0.687) | 0.005 (–0.016,0.026) | 0.620 (0.566,0.679) | –0.001 (–0.014,0.011) | –0.006 (–0.028,0.016) | 0.6216 (0.568,0.681) | 0.643 (0.591,0.700) | 0.022 (–0.011,0.054) |
Post-menopausal breast cancer | 0.576 (0.559,0.595) | 0.583 (0.565,0.601) | 0.006 (–0.006,0.018) | 0.584 (0.566,0.602) | 0.007 (–0.005,0.019) | 0.001 (–0.007,0.009) | 0.577 (0.559,0.595) | 0.584 (0.566,0.603) | 0.007 (–0.006,0.021) |
