Table 3 Results for the multivariate analysis are shown for TB assessment in 10 HPF and for overall survival.

From: Tumor budding and lymphovascular invasion as prognostic factors in p16-positive oropharyngeal squamous cell carcinomas

  

HR (mean)

HR (95% CI)

p

Age

 

1.06

1.01–1.11

0.011

Sex

    
 

Male

1

  
 

Female

0.9

0.34–2.42

0.841

UICC stage

    
 

Stage I/II

1

  
 

Stage III

1.94

0.22–17.01

0.551

 

Stage IV

3.63

0.42–31.15

0.240

Resection status

    
 

R0

1

  
 

R1/R2

2.12

0.74–6.08

0.162

 

RX

0.67

0.16–2.72

0.571

Lymphovascular invasion

    
 

Absent

1

  
 

Present

3.00

1.22–7.38

0.016

TILs

    
 

Low

1

  
 

High

0.46

0.15–1.45

0.186

Tumor budding

    
 

Low

1

  
 

High

4.03

1.65–9.83

0.002

  1. HR Hazard ratio, 95% CI 95% confidence interval, TILs Tumor infiltrating lymphocytes, UICC Union internationale contre le cancer.
  2. Bold values indicate statistical significance.