Fig. 4: Castration resistant tumor sensitive to EphB4 blockage.
From: EphB4-ephrin-B2 are targets in castration resistant prostate cancer
a BLI of luciferase expression in live mice at 4 months, 5.5-months, 8.5-months, 10-months and 14.5-months of age corresponding to time post-castration of 0, 1.5, 4.5, 6, and 10.5 months, respectively. Mice were treated with either PBS or sEphb4-alb from 8.5 months of age. Left panel: CPPL treated with PBS. Right panel: CPPL treated with sEphB4-alb. Three mice from each group are shown. Color bars indicate the intensity of luciferase signal. b Quantitative measurement of total BLI signal intensity of 8 CPPL;sEphB4-alb treated mice. BLI intensity is shown on the top of each bar. Error bars represent s.d.
