Fig. 7: SMAD2 linker phosphorylation in NSCLC affects OS and DFS in a spatially distinct manner. | British Journal of Cancer

Fig. 7: SMAD2 linker phosphorylation in NSCLC affects OS and DFS in a spatially distinct manner.

From: SMAD2 linker phosphorylation impacts overall survival, proliferation, TGFβ1-dependent gene expression and pluripotency-related proteins in NSCLC

Fig. 7: SMAD2 linker phosphorylation in NSCLC affects OS and DFS in a spatially distinct manner.The alternative text for this image may have been generated using AI.

a, b Categorised NSCLC patients according to pSMAD2L cell density in tumour and stroma areas dichotomised variables (high/low) were analysed to determine the impact on OS and DFS (time = months). c, d Relative frequency (%) of categorised NSCLC patients with high and low pSMAD2L cell density in tumour and stroma areas. e Schematic illustration of the pSMAD2L status in tumour (panCK+) and immune cells (CD45+) as well as the impact on prognosis (created with bioRender.com).

Back to article page