Table 3 Mutually-adjusted associations between differentiated thyroid cancer risk factors.
From: In-utero and newborn factors and thyroid cancer incidence in adult women in the Sister Study cohort
Characteristic | DTC cases, N | Person-years | HRa | 95% CIa |
|---|---|---|---|---|
Pre-pregnancy or gestational diabetes | ||||
Probably not/Definitely not | 230 | 562,673 | 1 | — |
Definitely/Probably | 5 | 5198 | 1.89 | 0.76, 4.67 |
Unknownb | 4 | 15,265 | – | – |
Gestational hypertension or hypertension-related disorders | ||||
Probably not/Definitely not | 199 | 490,021 | 1 | — |
Definitely/Probably | 16 | 19,753 | 2.00 | 1.19, 3.35 |
Unknownb | 24 | 73,361 | – | – |
Gestational age at birth | ||||
Born post-term or up to 2 weeks before the due date | 116 | 237,133 | 1 | — |
Born at least 2 weeks before the due date | 8 | 34,695 | 0.54 | 0.26, 1.15 |
Unknownb | 115 | 311,308 | – | – |
Birth weight (g) | ||||
<2500 | 10 | 42,933 | 0.7 | 0.36, 1.36 |
2500–3999 | 140 | 349,938 | 1 | — |
4000+ | 23 | 38,632 | 1.43 | 0.92, 2.24 |
Unknownb | 66 | 151,632 | – | – |