Table 1 Baseline characteristics.
Group | GX-I7 60 µg/kg (n = 3) | GX-I7 120 µg/kg (n = 3) | GX-I7240 µg/kg (n = 3) | GX-I7 480 µg/kg (n = 3) | GX-I7 720 µg/kg (n = 6) | GX-I7 960 µg/kg (n = 3) | GX-I7 1200 µg/kg (n = 12) | GX-I7 1700 µg/kg (n = 2) | Total (n = 35) |
|---|---|---|---|---|---|---|---|---|---|
Age (years) | |||||||||
Median (Min, Max) | 58 (52, 64) | 58 (55, 58) | 59 (52, 75) | 44 (44, 48) | 57 (45, 71) | 58 (45, 65) | 62 (43, 75) | 54 (48, 60) | 58 (40, 75) |
Gender, N (%) | |||||||||
Male | 2 (67) | 0 | 3 (100) | 2 (67) | 4 (67) | 1 (33) | 6 (50) | 1 (50) | 19 (54) |
Race, N (%) | |||||||||
Asian | 3 (100) | 3 (100) | 3 (100) | 3 (100) | 6 (100) | 3 (100) | 12 (100) | 2 (100) | 35 (100) |
ECOG performance status, N >(%) | |||||||||
0 | 1 (33) | 1 (33) | 1 (33) | 0 | 5 (83) | 2 (67) | 5 (42) | 2 (100) | 17 (49) |
1 | 2 (67) | 2 (67) | 2 (67) | 3 (100) | 1 (17) | 1 (33) | 7 (58) | 0 | 18 (51) |
Site of Primary Tumour, N (%) | |||||||||
Breast | 1 (33) | 0 | 0 | 1 (33) | 0 | 0 | 2 (17) | 0 | 4 (11) |
Colon/Rectal | 1 (33) | 2 (67) | 2 (67) | 2 (67) | 4 (67) | 3 (100) | 7 (58) | 2 (100) | 23 (66) |
Ovary | 0 | 1 (33) | 0 | 0 | 0 | 0 | 2 (17) | 0 | 3 (9) |
Other | 1 (33) | 0 | 1 (33) | 0 | 2 (33) | 0 | 1 (8) | 0 | 5 (14) |
Location of Metastatic, N | |||||||||
Abdominal Wall | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 4 |
Adrenal Gland | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3 |
Bone | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 4 |
Brain | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2 |
Liver | 2 | 2 | 2 | 2 | 1 | 3 | 10 | 2 | 24 |
Lung | 3 | 2 | 3 | 3 | 5 | 3 | 11 | 2 | 32 |
Lymph Node | 2 | 2 | 1 | 2 | 3 | 2 | 2 | 0 | 14 |
Pleura | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2 |
Other | 2 | 0 | 2 | 1 | 2 | 2 | 4 | 0 | 13 |
Previous illness of systemic therapy, N (%) | |||||||||
0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 (8)† | 0 | 1 (3) |
1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
2 | 0 | 0 | 1 (33) | 1 (33) | 1 (17) | 0 | 1 (8) | 0 | 4 (11) |
3 | 1 (33) | 0 | 0 | 0 | 4 (67) | 1(33) | 5 (42) | 2 (100) | 13 (37) |
≥4 | 2 (67) | 3 (100) | 2 (67) | 2 (67) | 1 (17) | 2 (67) | 5 (42) | 0 | 17 (49) |
