Table 3 Change in body weight, abdominal fat and muscle stores between baseline and cycle 3 (week 9 of the trial) in the IER + RE and RE groups.

From: Randomised phase-2 screening trial of intermittent energy restriction plus resistance exercise versus resistance exercise alone during chemotherapy for advanced breast cancer

Change between baseline and cycle 3

IER + RE (n = 35)

RE (n = 33)

All n = 68

P value IER + RE vs RE

N

n = 30

n = 30

N = 60

 

Body weight (kg)

–1.50 (–2.78, -0.60)

0.10 (–0.60, 1.90)

–0.70 (–1.94, 0.13)

<0.001

% Change

–1.78 (–4.19, -0.72)

0.15 (–0.74, 2.59)

–0.87 (–2.33, 0.18)

 

VAT mm2

–1002 (–2041, 330)

–378 (–1905, 1180)

–582 (–1991, 984)

0.143

% Change

–7.9 (–17.5, 7.9)

–3.2 (–12.7, 10)

–4.7 (–15.4, 9.2)

 

DSAT mm2

–751 (–1826, 111)

–14 (–1336, 1497)

–446 (–1530, 635)

0.232

% Change

–6.2 (–13.3, 0.9)

–0.2 (–10, 9.8)

–3.9 (–12.5, 6.0)

 

SSAT mm2

–870 (–2279, 495)

285 (–1481, 1446.)

–332 (–1852, 860)

0.115

% Change

–3.8 (–19.7, 7.7)

2 (–6.2, 7.4)

–3 (–16.4, 7.6)

 

Total SAT mm2

–1568 (–3452, 658)

–220 (–2256, 2356)

–994 (–2921, 1680)

0.281

% Change

–5.5 (–13.5, 2.1)

–0.9 (–5.4, 9.1)

–3.4 (–8.4, 5.7)

 

Total AT mm2

–2454.5 (–4233, 987)

276 (–3475, 3502)

–1454 (–4091, 2066)

0.176

% Change

–6.6 (–11.8, 2.3)

0.8 (–8.2, 8.8)

–3.7 (–9.4, 5.2)

 

Muscle mm2

–59 (–560, 217)

–153.5 (–587, 502)

–72 (–574, 285)

0.694

% Change

–0.6 (–5.4, 1.9)

–1.4 (–5.6, 4.4)

–0.8 (–5.6, 2.3)

 

Skeletal muscle index

–0.22 (–2.13, 0.75)

–0.57 (–2.33, 1.80)

–0.26 (–2.21, 1.06)

0.658

% Change

–0.6 (–5.4, 1.9)

–1.4 (–5.6, 4.4)

–0.8 (–5.6, 2.3)

 
  1. Median (interquartile range).
  2. VAT visceral adipose tissue, DSAT deep subcutaneous fat, SSAT superficial subcutaneous fat, SAT subcutaneous tissue, AT abdominal tissue.