Fig. 3: Forest plot of obesity-driven metabolites associated with cancer risk.

Odds ratios and 95% confidence intervals were estimated using MR utilising either the IVW-RE method or Wald ratio (depending on the number of IVs). The names of the metabolites are given in the left column, stratified by the associated cancer risk. The vertical dashed line indicates a null effect. The error bars show 95% confidence intervals around the estimated odds ratio. nSNP number of SNPs. Created using the forester (v0.3.0) R package [60]. HDL high-density lipoprotein, VLDL very-low-density lipoprotein, GPC glycero-phosphatidylcholine, GPE glycero-phosphatidylethanolamine, GPA glycero-phosphate.