Table 3 Types of molecular analysis performed.
lcWGS (Somatic) | WES (Somatic) | DNA panel sequencing | RNA-seq | DNA methylation profiling | Germline WGS | Germline WES | Others | |
|---|---|---|---|---|---|---|---|---|
Church et al. [7] | Targeted DNA panel (OncoPanel) | mRNA-Seq; RNA fusion panel | ||||||
Parsons et al. [23] | mRNA-Seq | DNA methylation profiling | Other: IHC assays | |||||
van Tilburg et al. [25] | lcWGS (Somatic) | WES (Somatic) | mRNA-Seq | DNA methylation profiling | RNA based gene expression array | |||
Villani et al. [26] | mRNA-Seq | Germline WGS | Other: pan-cancer DNA panel | |||||
Ortiz et al. [22] | WES (Somatic) | Targeted gene panel | ||||||
Pincez et al. [24] | NGS DNA gene panel | Other: CGH | ||||||
Mody et al. [20] | WES (Somatic) | mRNA-Seq | ||||||
Marks et al. [19] | WES (Somatic) | DNA sequencing of 467 cancer associated genes | mRNA-Seq | Germline WES | ||||
Oberg et al. [21] | WES (Somatic) | mRNA-Seq | DNA methylation profiling | Germline WES | ||||
George et al. [16] | circulating tumour DNA (ctDNA), Targeted NGS genetic panel | Germline WES | ||||||
Harris et al. [27] | Targeted NGS (OncoPanel) | |||||||
De Abreu Lourenco et al. [14] | Genomically guided approach, no specific information given | |||||||
McCullough et al. [28] | WES (Somatic) | Germline WES | ||||||
Harttrampf et al. [17] | WES (Somatic) | mRNA-Seq | ||||||
Eaton et al. [15] | Germline WGS | Functional ex vivo drug sensitivity testing | ||||||
McCarthy [29] | Genomically guided approach, no specific information given | |||||||
Langenberg et al. [18] | lcWGS (Somatic) | WES (Somatic) | mRNA-Seq | DNA methylation profiling | Affymetrix gene expression | |||
Light grey = somatic | ||||||||
Dark Grey = germline | ||||||||
