Fig. 6: Comparative evaluation of molecular diagnostic approaches in the cohort. | British Journal of Cancer

Fig. 6: Comparative evaluation of molecular diagnostic approaches in the cohort.

From: Benchmarking standard-of-care and emerging genomic approaches to enhance diagnosis in pediatric acute lymphoblastic leukemia

Fig. 6

a Sankey diagram showing the distribution and reclassification of patients across four diagnostic strategies: standard-of-care, standard-of-care with t-NGS, dMLPA combined with t-NGS, and OGM. Each vertical axis represents one diagnostic approach, while the coloured flows depict how individual patient classification shifts among categories with each successive approach. b Risk stratification comparison across methodologies, showing the proportion of patients classified into different genetic risk groups. The width of each node is proportional to the number of patients in each category.

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