Fig. 2: Univariate associations of IL10, IL6, and IL8 with survival in advanced disease.

KaplanāMeier plots are shown for illustrative purposes only. Data were analysed continuously using the method of fractional polynomials (TableĀ 3). Relations are shown between a PFS and b OS for IL10; c PFS and d OS for IL6; e PFS and f OS for IL8. Patients were stratified by quartile of cytokine levels.