Table 1 Characteristics of patients who received systemic chemotherapy.

From: Survival outcomes of ERBB2-amplified metastatic colorectal cancer treated with first-line chemotherapy

Factor

Category

ERBB2 amp+

ERBB2 amp−

p-value

n = 144

n = 4604

Age

Median (range)

58 (28-83)

61 (20-85)

<0.01

Sex

Male

87 (60%)

2484 (54%)

0.13

 

Female

57 (40%)

2120 (46%)

 

Initial Stage

I–III

35 (25%)

1215 (26%)

0.58

 

IV

105 (72%)

3300 (72%)

 
 

Unknown

5 (3%)

85 (2%)

 

Race/Ethnicity

Hispanic or Latino

11 (8%)

234 (5%)

0.50

 

Not Hispanic or Latino, White

81 (56%)

2656 (58%)

 
 

Not Hispanic or Latino, Black or African American

13 (9%)

383 (8%)

 
 

Not Hispanic or Latino, Asian/Other Race/Unknown Race

18 (13%)

527 (11%)

 
 

Unknown

21 (14%)

804 (18%)

 

Primary location

Left-sided

64 (45%)

1965 (42%)

<0.01

 

Right-sided

15 (10%)

1039 (22%)

 
 

Unknown

65 (45%)

1600 (35%)

 
  1. Age denotes age at metastatic diagnosis. The race/ethnicity variable categorises ‘Hispanic or Latino’ as all Hispanic/Latino individuals regardless of race, while White, Black and Asian are limited to non-Hispanic individuals. ‘Asian/Other Race/Unknown Race’ includes patients with race categories masked due to small counts. Primary location (tumour sidedness) was determined using the International Classification of Diseases codes 9 and 10. Initial stage values are rounded to the nearest 5 to mask small counts.
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