Table 1 Patients’ characteristics.

From: Lymphocyte subset reconstitution and clinical outcomes following haploidentical hematopoietic stem cell transplantation

Characteristic

All patients (n = 577)

Median patient age, year (range)

40 (6–71)

Median donor age, year (range)

32 (8–69)

Patient sex

 Male

346 (60.0%)

 Female

231 (40.0%)

Donor sex

 Male

386 (66.9%)

 Female

191 (33.1%)

Patient–donor sex

 Female to male

104 (18.0%)

 Others

473 (82.0%)

GVHD prophylaxis

 ATG + CSA + MTX + MPA

170 (29.5%)

 ATG + CSA + CTX + MPA

340 (58.9%)

 CTX + CSA + MPA

67 (11.6%)

Conditioning regimens

 MAC

439 (76.1%)

 RIC

138 (23.9%)

Diagnosis

 AML

298 (51.6%)

 ALL

104 (18.0%)

 MDS

102 (17.7%)

 NHL

73 (12.7%)

Risk stratification

 Low risk

107 (18.5%)

 Intermediate risk

152 (26.3%)

 High risk

318 (55.1%)

Disease status

 CR

445 (77.1%)

 NR

132 (22.9%)

ECOG

 0

392 (67.9%)

 1

162 (28.1%)

 2

15 (2.6%)

 3–4

8 (1.4%)

HCT-CI

 <3

550 (95.3%)

 ≥3

27 (4.7%)

Median CD34+ cell (×106/kg), range

11.12 (1.58–46.55)

Median CD3 + T cell (×108/kg), range

3.30 (0.61–10.8)

  1. GvHD graft-versus-host disease, CSA cyclosporine, MTX methotrexate, MPA mycophenolate, ATG rabbit-anti-human thymocyte globulin, CTX cyclophosphamide, MAC myeloablative conditioning, RIC reduced-intensity conditioning, AML acute myeloid leukaemia, ALL acute lymphoblastic leukaemia, MDS myelodysplasia syndrome, NHL non-Hodgkin lymphoma, CR complete remission, NR non-complete remission, ECOG Eastern cooperative oncology group, HCT-CI hematopoietic cell transplantation comorbidity index.