Table 3 Association between lymphocyte subset reconstitution and transplant-related mortality.

From: Lymphocyte subset reconstitution and clinical outcomes following haploidentical hematopoietic stem cell transplantation

Lymphocyte subsets

Median (cells/μL)

5-year TRM (95% CI)

HR (95% CI)

P

> median

<median

Treg at 1 m

1.3

6.7% (0–13.2%)

20.5% (10.3–29.6%)

0.20 (0.09–0.82)

0.021

Treg at 2 m

3.4

4.1% (0.04–8.0%)

19.9% (10.0–28.8%)

0.20 (0.07–0.58)

0.004

Treg at 4 m

6

3.0% (0–6.2%)

12.0% (5.1–18.3%)

0.24 (0.07–0.81)

0.028

naïve CD8+ T cell at 1 m

14.1

15.5% (2.0–27.1%)

20.2% (10.0–29.4%)

0.34 (0.13–0.87)

0.025

naïve CD8+ T cell at 3 m

120.6

10.5% (1.3–18.8%)

14.6% (8.5–20.3%)

0.40 (0.18–0.87)

0.020

naïve CD8+ T cell at 9 m

231.5

1.9% (0–4.5%)

14.7% (4.8–23.5%)

0.11 (0.02–0.50)

0.004

NK cell at 2 m

191.5

5.7% (1.8–9.4%)

17.5% (9.9–24.5%)

0.35 (0.16–0.80)

0.012

B cell at 2 m

60.2

6.5% (2.3–10.5%)

16.3% (9.2–22.7%)

0.40 (0.18–0.89)

0.025

B cell at 3 m

46.2

4.8% (1.2–8.3%)

22.0% (11.4–31.4%)

0.38 (0.14–0.99)

0.048

B cell at 4 m

62.9

9.5% (0–21.9%)

16.7% (8.5–24.2%)

0.28 (0.10–0.80)

0.024

B cell at 6 m

112.2

8.4% (0–18.9%)

18.5% (10.0–26.1%)

0.30 (0.11–0.80)

0.017

B cell at 9 m

186

5.3% (0–13.4%)

11.5% (4.8–17.7%)

0.21 (0.05–0.90)

0.044