Table 3 Association between lymphocyte subset reconstitution and transplant-related mortality.
Lymphocyte subsets | Median (cells/μL) | 5-year TRM (95% CI) | HR (95% CI) | P | |
|---|---|---|---|---|---|
> median | <median | ||||
Treg at 1 m | 1.3 | 6.7% (0–13.2%) | 20.5% (10.3–29.6%) | 0.20 (0.09–0.82) | 0.021 |
Treg at 2 m | 3.4 | 4.1% (0.04–8.0%) | 19.9% (10.0–28.8%) | 0.20 (0.07–0.58) | 0.004 |
Treg at 4 m | 6 | 3.0% (0–6.2%) | 12.0% (5.1–18.3%) | 0.24 (0.07–0.81) | 0.028 |
naïve CD8+ T cell at 1 m | 14.1 | 15.5% (2.0–27.1%) | 20.2% (10.0–29.4%) | 0.34 (0.13–0.87) | 0.025 |
naïve CD8+ T cell at 3 m | 120.6 | 10.5% (1.3–18.8%) | 14.6% (8.5–20.3%) | 0.40 (0.18–0.87) | 0.020 |
naïve CD8+ T cell at 9 m | 231.5 | 1.9% (0–4.5%) | 14.7% (4.8–23.5%) | 0.11 (0.02–0.50) | 0.004 |
NK cell at 2 m | 191.5 | 5.7% (1.8–9.4%) | 17.5% (9.9–24.5%) | 0.35 (0.16–0.80) | 0.012 |
B cell at 2 m | 60.2 | 6.5% (2.3–10.5%) | 16.3% (9.2–22.7%) | 0.40 (0.18–0.89) | 0.025 |
B cell at 3 m | 46.2 | 4.8% (1.2–8.3%) | 22.0% (11.4–31.4%) | 0.38 (0.14–0.99) | 0.048 |
B cell at 4 m | 62.9 | 9.5% (0–21.9%) | 16.7% (8.5–24.2%) | 0.28 (0.10–0.80) | 0.024 |
B cell at 6 m | 112.2 | 8.4% (0–18.9%) | 18.5% (10.0–26.1%) | 0.30 (0.11–0.80) | 0.017 |
B cell at 9 m | 186 | 5.3% (0–13.4%) | 11.5% (4.8–17.7%) | 0.21 (0.05–0.90) | 0.044 |