Fig. 3: The cohesin complex.

A diagram of the mitotic cohesin complex showing the somatic mutations detected by exome sequencing observed in the MCM cases. Meiosis-specific components are essential for proper chromosome behaviour during meiotic cell division, these components are shown in brackets. The codon locations are highlighted in orange in the genes SMC3, SMC1A, and STAG3. Created in https://BioRender.com.