Fig. 6: MRI scans, CSF cytology and ctDNA analysis of patients with LM with failed treatment responses to third-generation EGFR-TKIs at different clinical time points. | British Journal of Cancer

Fig. 6: MRI scans, CSF cytology and ctDNA analysis of patients with LM with failed treatment responses to third-generation EGFR-TKIs at different clinical time points.

From: Furmonertinib combined with bevacizumab in EGFR-TKI-resistant leptomeningeal metastasis: analysis of the CSF ctDNA molecular response and survival outcomes

Fig. 6: MRI scans, CSF cytology and ctDNA analysis of patients with LM with failed treatment responses to third-generation EGFR-TKIs at different clinical time points.The alternative text for this image may have been generated using AI.

a Dynamic changes in MRI scans, CSF cytology and ctDNA. b Dynamic changes in the allele frequency of various mutations detected in serial CSF samples. MRI magnetic resonance imaging, CSF cerebrospinal fluid, ctDNA circulating tumour DNA, LM leptomeningeal metastasis, EGFR epidermal growth factor receptor, TKI tyrosine kinase inhibitor.

Back to article page