Fig. 4: Immunohistochemistry analyses of eccrine porocarcinoma tissue reveal deregulation of the HRR component BRCA2.
From: Whole-exome sequencing in eccrine porocarcinoma indicates promising therapeutic strategies
a Representative images of positive (left panel) and negative (right panel) BRCA2 staining in EP tumour tissue. All images are shown at ×100 magnification. The inlays are shown at ×400 magnification. Scale bar in the bottom left corner indicates 100 µm. Representative images of the positive control are displayed Supplemental Fig. S1. b IHC analyses of 11 EP tumours reveal diverse BRCA2 staining. A qualitative score of 0 (no colour reaction), 1 (mild reaction), 2 (moderate reaction), and 3 (intense reaction) was assigned and displayed in an XY graph.
