Fig. 1: TMEM158 mRNA is highly expressed in IDH1-WT GBMs and is correlated with poor prognosis in glioma patients. | Cancer Gene Therapy

Fig. 1: TMEM158 mRNA is highly expressed in IDH1-WT GBMs and is correlated with poor prognosis in glioma patients.

From: TMEM158 promotes the proliferation and migration of glioma cells via STAT3 signaling in glioblastomas

Fig. 1: TMEM158 mRNA is highly expressed in IDH1-WT GBMs and is correlated with poor prognosis in glioma patients.

A Expression profile of TMEM158 in 31 kinds of cancers and their paired normal tissues from TCGA database. B–D Relationship between TMEM158 mRNA expression and WHO glioma grades and IDH1 mutation status of glioma samples in the TCGA and CGGA databases. E–G Expression of TMEM158 in IDH1-Mut-codel LGG, IDH1-Mut-noncodel LGG, IDH1-WT LGG, IDH1-Mut GBM, and IDH1-WT GBM. H–J TCGA and CGGA datasets were used for survival analysis of the two groups of glioma patients with higher TMEM158 expression and lower TMEM158 expression in glioma patients. K–L Kaplan–Meier survival curves were used to analyze the overall survival of GBM patients with higher expression of TMEM158 and lower expression of TMEM158 in the TCGA Agilent and U133A databases. (nsp > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001).

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