Fig. 6: Expression of TP53 target genes is positively correlated with AATK expression in cancer. | Cancer Gene Therapy

Fig. 6: Expression of TP53 target genes is positively correlated with AATK expression in cancer.

From: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner

Fig. 6

Pearson correlation of AATK and BAX, BBC3 (PUMA) or CDKN1A (p21) expression in breast cancer, colon adenocarcinoma, lung cancer (adeno- and squamous cell carcinoma) and pancreatic adenocarcinoma was analyzed via GEPIA [45] (TPM = transcripts per million).

Back to article page