Fig. 6: Overexpression of ANRIL decreased the effect of PZH on cancer cells, and the regulation of cancer cells on HLECs.

A The colony formation, migration, invasion abilities of HCT-8/ANRIL cells with or without 0.75 mg/mL PZH treatment, compared with HCT-8/Vector cells with or without 0.75 mg/mL PZH treatment. B The cell viability, migration, invasion and tube formation abilities of HLECs incubated with supernatants of HCT-8/ANRIL cells with or without 0.25 mg/mL PZH treatment, compared with HCT-8/Vector cells with or without 0.25 mg/mL PZH treatment. Data represent the mean ± SD of experiments conducted in triplicate experiments. One-way ANOVA followed by Tukey’s test was used to evaluate the statistical significance, different letters represent significant differences between different groups (P < 0.05).