Table 1 Metastasis profile of orthotopic prostate cancer murine models.

From: Inhibition of orthotopic castration-resistant prostate cancer growth and metastasis in mice by JC VLPs carrying a suicide gene driven by the PSA promoter

Groups

Local Growth

Lung Mets*

Liver Mets

Spleen Mets

Digestive system Mets

Kidney Mets

Femur Mets

MOCK

n = 4

4/4 (100%)

2/4 (50%)

1/4 (25%)

2/4 (50%)

3/4 (75%)

0/4 (0%)

0/4 (0%)

VLP/GCV

n = 4

4/4 (100%)

2/4 (50%)

0/4 (0%)

0/4 (0%)

2/4 (50%)

0/4 (0%)

0/4 (0%)

PSAtk-VLP/GCV

n = 4

4/4 (100%)

1/4 (25%)

0/4 (0%)

0/4 (0%)

2/4 (50%)

0/4 (0%)

0/4 (0%)

  1. 22Rv1-iRFP-tGFP cancer cells were implanted using orthotopic routes. Columns represent number of mice with local growth at orthotopic site, or metastases at necropsy. (*Mets: Metastasis).
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