Table 1 Baseline characteristics in 7 relapsed/refractory multiple myeloma patients.

From: An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously

Patient No.

Age (years)

Gender

Monoclonal Protein

Serum Monoclonal protein level (g/L)

Extramedullary disease

Previous lines

Previous ASCT

Previous CAR-T infusion

Previous CAR-T dose (×106/kg)

Bone marrow plasma cells (%)

BCMA in plasma cells (%)

HRC0202 dose (×106/kg)

1

51

Male

IgD-λ

2.55

No

7

Yes

HDS269B, HRC0202

HRC0202: 12

77.40

89.01

10

2

57

Male

IgG-κ

1.60

No

4

No

HRC0501

6

0.12

0.18

15

3

72

Female

IgA-κ

2.13

No

6

No

HDS269B

9

5.23

48.64

15

4

50

Male

IgG-κ

6.09

No

8

No

HDS269B, HRC0501

HRC0501: 6

0.67

0.00

15

5

57

Female

IgG-λ

2.77

Yes

4

No

HRC0501

6

0.19

2.00

6

6

54

Female

IgA-λ

16.50

No

11

No

HRC0501

6

0.64

17.07

6

7

51

Female

IgG-κ

4.95

Yes

7

No

HRC0501

3

0.13

2.65

6

  1. The table shows study baseline characteristics, including demography, disease, previous treatment, previous CAR-T and HRC0202 infusion. ASCT, autologous hematopoietic stem cell transplantation; HDS269B: murine-derived anti-BCMA CAR-T; HRC0202: fully human anti-BCMA CAR-T; HRC0501: murine-derived anti-BCMA/CD19 bispecific CAR-T.