Fig. 5: The oncogenic GnaqQ209L mutation sensitizes the immortalized melanocyte line Melan-a for Hgf-Met signaling. | Cancer Gene Therapy

Fig. 5: The oncogenic GnaqQ209L mutation sensitizes the immortalized melanocyte line Melan-a for Hgf-Met signaling.

From: Transactivation of Met signaling by oncogenic Gnaq drives the evolution of melanoma in Hgf-Cdk4 mice

Fig. 5: The oncogenic GnaqQ209L mutation sensitizes the immortalized melanocyte line Melan-a for Hgf-Met signaling.

a Crystal violet assay of Melan-a Gnaqwt and GnaqQ209 cells treated with the indicated concentrations of Hgf for 72 h. b Western blot of Melan-a cells expressing Gnaqwt or GnaqQ209L treated with PMA and/or Hgf for the times indicated. All experiments were performed in triplicates, the data shown are representative images from one experiment.

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