Fig. 2: The vertebrate telomere complex. | Cancer Gene Therapy

Fig. 2: The vertebrate telomere complex.

From: Understanding, diagnosing, and treating pancreatic cancer from the perspective of telomeres and telomerase

Fig. 2: The vertebrate telomere complex.The alternative text for this image may have been generated using AI.

The telomere has a T-loop and D-loop structure, which is divided into 3 ‘and 5’ ends at the end. There is a Shelterin complex on the telomeres, which helps maintain stability. POT1 protection of telomeres 1. RAP1 repressor/activator protein 1. TIN2 TERF1-interacting nuclear factor 2. TPP1 telomere protection protein 1. TRF1 telomeric repeat binding factor 1. TRF2 telomeric repeat binding factor 2.

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