Fig. 1: Pathological role of ion channels and transporters in hepatocellular carcinoma.
From: Pathophysiological role of ion channels and transporters in hepatocellular carcinoma
Altered and dysfunctional hydrogen ion channels, calcium ion channels, potassium ion channels, chloride ion channels, acid-sensitive ion channels, and water channels have implications for proliferation, migration, invasion, and apoptosis in hepatocellular carcinoma. NHE1 Na(+)/H(+) exchanger type 1 isoform, ASICs acid-sensing ion channels, CLIC1 intracellular chloride channel 1, AQP3 aquaporin 3, AQP9 aquaporin 9, TRAM-34 triarylmethane-34, ERK extracellular signal-regulated kinase.
