Fig. 6: Inflammatory gene expression dynamically improved, and immune-related pathways activated during the treatment in the responsive MSS CRC patient. | Cancer Gene Therapy

Fig. 6: Inflammatory gene expression dynamically improved, and immune-related pathways activated during the treatment in the responsive MSS CRC patient.

From: The long-term effectiveness and mechanism of oncolytic virotherapy combined with anti-PD-L1 antibody in colorectal cancer patient

Fig. 6

A Increased expression of T-cell activation-associated genes in the responder. B–E GSEA analysis of T-cell activation and immune response pathways, showing enrichment scores for αβ T-cell differentiation, leukocyte chemotaxis, regulation of αβ T-cell activation, and regulation of adaptive immune response. F Dynamic changes of WES data in responder. G Dynamic changes of different gene mutation types in responder.

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