Fig. 4: Knocking out Cav-1 affects gene expression involved in epithelial cell migration. | Cancer Gene Therapy

Fig. 4: Knocking out Cav-1 affects gene expression involved in epithelial cell migration.

From: Caveolin-1 knockout mitigates breast cancer metastasis to the lungs via integrin α3 dysregulation in 4T1-induced syngeneic breast cancer model

Fig. 4: Knocking out Cav-1 affects gene expression involved in epithelial cell migration.

A Heatmap demonstrating that knocking out Cav-1 expression significantly affected 53 genes at week 2 and 49 genes at week 3. B Heatmap showing DEG, which is known to be involved in epithelial cell migration and expressed at specific time points in either week 2 or week 3. DESeq at threshold DESeq2, P-value ≤ 0.05.

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