Fig. 5: Serum biochemistry and hematology in hamsters after Adf35(OGN) treatment. | Cancer Gene Therapy

Fig. 5: Serum biochemistry and hematology in hamsters after Adf35(OGN) treatment.

From: Biodistribution and toxicity evaluation of oncolytic adenovirus Adf35(OGN) in Syrian hamster and mouse

Fig. 5

Hamsters were injected subcutaneously with Adf35(Mock) and Adf35(OGN). Untreated and PBS-injected hamsters served as controls. Analyses including biochemistry (A) and hematology (B) were performed on samples harvested at either early (E) or late (L) termination points as indicated. Individual values from each animal, as well as mean ± SD are shown. Mann–Whitney U and Kruskal–Wallis tests were used to identify any statistically significant differences between virus treated groups and controls. Individuals with hemolysis index above three are marked with a black circle where relevant. GMP: GMP grade, LAB: laboratory grade.

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