Table 1 Demographic and clinical characteristics of controls and PMP patients included.

From: Exploring RNA biology in pseudomyxoma peritonei uncovers splicing dysregulation as a novel, targetable molecular vulnerability

 

Non-tumor

Tumor

  

Low grade

High grade

Patients, [n]

11

10

8

Age, [median (IQR)]

53 (28-68)

62.5 (48-76)

60 (48-71)

Women, (%)

45.5

60

50

Adjuvant treatment, (%)

20

37.5

Morbidity, [Clavien–Dindo 1-5 (%)]

1: 30

1: 25

2-5: 70

2-5: 75

Elevated CEA, (%)

55.6

12.5

Elevated CA9.9, (%)

22.2

12.5

Elevated CA125, (%)

33.3

14.3

Peritoneal Cancer Index, [median (IQR)]

31 (23-39)

22 (13-39)

Residual Disease, completeness of cytoreduction (CC), (%)

CC0-CC1: 80

CC0-CC1: 75

CC2-CC3: 20

CC2-CC3: 25

Ki67, [median (IQR)]

15 (10-22.5)

30 (15-50)

Recurrence, (%)

22.2

12.5

Months of Relapse-Free Survival, [median (IQR)]

26 (21.5-28.5)

14 (11-18)

Death, (%)

20

28.6

Months of Overall Survival, [median (IQR)]

23 (21.25-28)

15 (9.5-19)

  1. IQR Interquartile Range, CEA Carcinoembryonic Antigen, CA9.9 Carbohydrate Antigen 9.9, CA125 Carbohydrate Antigen 125, CC Completeness of Cytoreduction.