Fig. 1: LMTK3 regulates angiogenesis in a cell-type-dependent manner. | Cancer Gene Therapy

Fig. 1: LMTK3 regulates angiogenesis in a cell-type-dependent manner.

From: LMTK3 regulates breast cancer angiogenesis via a context-dependent mesenchymal-epithelial transition program

Fig. 1

A scRNA-seq analysis of angiogenesis scores and LMTK3 expression across BC subtypes (TNBC, ER + , HER2 + ). (P < 0.001, indicated by ***). B Violin and scatter plots of LMTK3 expression with angiogenesis scores within each subtype (epithelial and mesenchymal). C, D HUVEC tube formation assays using CM from WT and LMTK3-OE cells. (*P < 0.05, **P < 0.01, ***P < 0.001). E ELISA quantification of secreted angiogenin levels in T-47D/MCF-7/MDA-MB-231 WT and LMTK3-OE cells.

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