Fig. 3: Intracerebroventricular injection of the miR-3473b antagomir inhibited neuroinflammation following MCAO | Cell Death & Disease

Fig. 3: Intracerebroventricular injection of the miR-3473b antagomir inhibited neuroinflammation following MCAO

From: miRNA-3473b contributes to neuroinflammation following cerebral ischemia

Fig. 3

a mRNA levels of pro-inflammatory factors (iNOS, COX-2, TNF-α, and IL-6) in the cortical penumbra of mice receiving ICV injection of either the miR-3473b or NC antagomirs (n = 4). b Western blot and ELISA results showed that the miR-3473b antagomir but not the NC antagomir inhibited post-ischemic induction of the COX-2, IL-6, and TNF-α proteins in the ischemic penumbra (n = 3 per group). Sham: Sham operated groups; Contra: contralateral side; Ipsil: ipsilateral side. *P < 0.05, **P < 0.01; compared with NC

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