Fig. 3: miR-21 protects OGD/R-induced neuronal death | Cell Death & Disease

Fig. 3: miR-21 protects OGD/R-induced neuronal death

From: Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate ischemic neuronal death by targeting miR-21/PDCD4 signaling pathway

Fig. 3

a The modulation of miR-21 levels by scramble RNA, miR-21 mimic or miR-21 inhibitor in N2a cells were confirmed by qRT-PCR. Data are means ± S.E.M. for 3 independent experiments. * P < 0.05, ** P < 0.01, by Student’s t-test. b Apoptotic cell death of N2a cells transfected with scramble RNA, miR-21 mimic or miR-21 inhibitor was measured by TUNEL staining at 24 h after OGD treatment. Scale bar, 25μm. c Bar graph summarizes the number of TUNEL+ cells in different groups. Data are means ± S.E.M. for 5 cultures per group. * P < 0.05 by Student’s t-test

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