Fig. 5: Effects of FEZF1-AS1 or ZNF312B knockdown on the inhibition of PDAC cell proliferation and colony formation could be rescued by miR-107 inhibitor in vitro | Cell Death & Disease

Fig. 5: Effects of FEZF1-AS1 or ZNF312B knockdown on the inhibition of PDAC cell proliferation and colony formation could be rescued by miR-107 inhibitor in vitro

From: FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma

Fig. 5

a, b The expression of FEZF1-AS1 or ZNF312B was suppressed by specific siRNAs in PANC-1 and Capan-2 cells. c, d The cell viability of si-NC, si-FEZF1-AS1, si-NC + miR-107 inhibitor, si-FEZF1-AS1 + miR-107 inhibitor, or si-ZNF312B transfected PANC-1 and Capan-2 cells by CCK-8 assay. e The proliferation of si-NC, si-FEZF1-AS1, si-NC + miR-107 inhibitor, si-FEZF1-AS1 + miR-107 inhibitor, or si-ZNF312B transfected PANC-1 and Capan-2 cells by colony formation assay. Values represented the mean ± SD from three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, Student’s t-test

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