Fig. 5: BCL-XL protein expression correlates with invasion and migration in a panel of melanoma cell lines
From: BCL-XL overexpression promotes tumor progression-associated properties
Western blotting analysis BCL-XL protein expression in (a) melanoma and (c) glioblastoma cell lines. Reported images are representative of two independent experiments with similar results. β-actin expression was evaluated to confirm equivalent transfer and loading. (b, d) Correlation among BCL-XL evaluated via Western blotting analysis and invasion/migration properties in a panel of melanoma (b) and glioblastoma (d) cell lines. Densitometric values of normalized BCL-XL protein level were plotted against the number of migrated/invaded cells. Arrows indicate cell lines with highest (M20) and lowest (JR8, SAN) migration/invasion properties. JR8 and SAN cells showed superimposable values. Results were considered to be statistically significant if *p  < 0.05. e Tumor sphere-forming capacity evaluated in Mneo, MXL90 and M20 cells. Data were expressed as average ± standard deviation
