Fig. 2: Sirt6 overexpression attenuated replicative senescence of rat NP cells | Cell Death & Disease

Fig. 2: Sirt6 overexpression attenuated replicative senescence of rat NP cells

From: Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Fig. 2

We passaged NP cells to the 15th generations to detect sirt6 and p16. a SA-β-gal staining assay was performed in NP cells of each group (scale bar: 50 μm). b–d Representative western blots and quantification data of p16 and sirt6 in human NP cells of each group; columns represent mean ± SD. Significant differences between the treatment and sham groups are indicated as **P < 0.01, ***P < 0.001, n = 5

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