Fig. 3: Sirt6 overexpression suppressed IL-1β-induced premature senescence and apoptosis of human NP cells | Cell Death & Disease

Fig. 3: Sirt6 overexpression suppressed IL-1β-induced premature senescence and apoptosis of human NP cells

From: Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Fig. 3

a–e Representative western blots and quantification data of p16, cleaved caspase3, Bax, Bcl-2 in NP cells of each group as treated above; columns represent mean ± SD. Significant differences between the treatment and control groups are indicated as *P < 0.05, **P < 0.01, ***P < 0.001, n = 5

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