Fig. 6: Sirt6 inhibits stress-induced premature senescence via autophagy | Cell Death & Disease

Fig. 6: Sirt6 inhibits stress-induced premature senescence via autophagy

From: Sirt6 overexpression suppresses senescence and apoptosis of nucleus pulposus cells by inducing autophagy in a model of intervertebral disc degeneration

Fig. 6

a SA-β-gal staining assay was performed in NP cells of each group as treated above (scale bar: 50 μm). b–e Representative western blots and quantification data of p-p53, p53, p21, and p16 in NP cells of each group as treated above; columns represent mean ± SD. Significant differences between the treatment and control groups are indicated as *P < 0.05, **P < 0.01, ***P < 0.001, n = 5

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