Fig. 1: PLZF was downregulated in GBC and correlated with overall survival
From: PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2
a qRT-PCR showed relative PLZF mRNA level was significantly lower in GBC tissues than those in adjacent non-neoplastic tissues. b Representative IHC staining images of normal gallbladder (NGB) and GBC tissues. c Quantification of PLZF expression according to IHC scores (see below) in NGB (n = 20) and GBC (n = 40). d Representative IHC staining images of different scores, which were calculated by intensity and percentage of stained cells as described in the methods. e GBC patient survival was analyzed by Kaplan–Meier analysis. P-value was calculated using log-rank test. Results showed lower expression of PLZF correlated with poorer prognosis
