Fig. 5: IFIT2 knockdown reversed the function of PLZF in NOZ cells | Cell Death & Disease

Fig. 5: IFIT2 knockdown reversed the function of PLZF in NOZ cells

From: PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2

Fig. 5: IFIT2 knockdown reversed the function of PLZF in NOZ cells

a, d CCK-8 assay was conducted in NOZ and GBC-SD cells transfected with MOCK + siControl, MOCK + siIFIT2, PLZF + siControl and PLZF + siIFIT2. b, e Colony formation assay was conducted in NOZ and GBC-SD cells transfected with MOCK + siControl, MOCK + siIFIT2, PLZF + siControl and PLZF + siIFIT2. Relative clone numbers are shown. c, f Transwell migration and matrigel invasion assays were conducted in NOZ cells transfected with MOCK + siControl, MOCK + siIFIT2, PLZF + siControl and PLZF + siIFIT2. Relative cell numbers are shown. g, i Expression of EMT markers and p21 were detected by qRT-PCR in GBC cells transfected with MOCK + siControl, MOCK + siIFIT2, PLZF + siControl and PLZF + siIFIT2. h, j Expression of EMT markers and p21 were detected by western blot. (P < 0.05)

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