Table 2 Univariate and multivariate analysis of the correlation of prognosis with PLZF and clinicopathologic data in GBC

Sex (male vs. female)

1.13 (0.67–1.92)

0.646

Age (<65 vs. ≥65)

1.24 (0.76–2.02)

0.39

Histological grade (III–IV vs. I–II)

1.18 (0.72–1.94)

0.501

Tumor size (≥4 vs. <4)

1.71 (1.05–2.82)

0.033*

1.32 (0.75–2.33)

0.328

TNM stage (III–IV vs. I–II)

2.27 (1.36–3.77)

0.002*

1.47 (0.73–2.94)

0.281

Lymph node metastasis (presence vs. absence)

2.16 (1.25–3.72)

0.006*

1.41 (0.68–2.94)

0.359

Distant metastasis (presence vs. absence)

2.36 (1.42–3.91)

0.001*

1.20 (0.55–2.63)

0.648

PLZF expression (high vs. low)

0.47 (0.28–0.80)

0.005*

0.48 (0.28–0.83)

0.008*