Table 2 Effect of HOTTIP on SCLC cell resistance index

From: Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a

 

IC50 (μg/ml ±S)

Cell groups

ADM

CDDP

VP-16

H69AR/si-HOTTIP

25.33 ± 5.51

29.0 ± 3.606

119.3 ± 15.01

 H69AR/si-NC

52.0 ± 9.17

56.0 ± 11.53

216.67 ± 10.69

 H69AR

45.67 ± 7.77

61.33 ± 16.50

237.3 ± 12.50

H446AR/si-HOTTIP

28.67 ± 6.51

46.33 ± 10.69

128.3 ± 2.89

 H446AR/si-NC

104.67 ± 15.5

135.33 ± 5.69

337.67 ± 52.3

 H446AR

98.33 ± 11.5

144.3 ± 10.07

292.33 ± 11.24

H69/pcDNA3.1+HOTTIP

75.33 ± 8.50

87.3 ± 3.51

229.00 ± 16.52

 H69/pcDNA3.1+NC

25.67 ± 5.03

33.0 ± 7.21

134.33 ± 6.02

 H69

19.0 ± 2.0

32.0 ± 3.0

161.33 ± 12.06

H446/pcDNA3.1+HOTTIP

117.3 ± 18.2

145.67 ± 7.09

214.33 ± 8.15

 H446/pcDNA3.1+NC

45.0 ± 6.0

53.33 ± 12.42

105.0 ± 22.72

 H446

42.3 ± 4.51

55.67 ± 11.06

111.67 ± 10.41

  1. ADM adriamycin, CDDP cisplatin, VP-16 etoposide
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