Fig. 2: Balance between autophagy and apoptosis: apoptosis is downregulated by autophagy | Cell Death & Disease

Fig. 2: Balance between autophagy and apoptosis: apoptosis is downregulated by autophagy

From: Cellular death, reactive oxygen species (ROS) and diabetic complications

Fig. 2

The activation of mTORC1 depends on PKC, which is activated by DAG. Thus, PKC in conjunction with ROS and mTORC1 pathway are associated in the control of cellular autophagy.

Akt/mammalian target of rapamycin complex 1 = mTORC1, ROS reactive oxygen species, PKC = protein kinase C, DAG = diacylglycerol.

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